N-acetylcysteine (NAC) in the treatment of Obsessive-compulsive disorder (OCD)
The University of Melbourne is currently conducting a 24-week (6 month) clinical trial investigating the effects of an amino acid supplement called N-acetylcysteine (NAC) in the treatment of Obsessive-Compulsive Disorder (OCD).
NAC is a particular amino acid which has been researched for various mental health disorders including depression, bipolar disorder, schizophrenia, addiction (nicotine, marijuana, gambling) as well as OCD. NAC has anti-inflammatory and antioxidant activity, and influences various neurochemicals in the brain including glutamate. Previous research studies indicate that these properties of NAC may be effective for OCD, however, more research studies are required to determine this.
If you are eligible to participate in the study, you will be randomly allocated into the NAC group OR a placebo group (dummy capsules). You will be given capsules (NAC or placebo) to take morning and night for the 6-month study period and these capsules will be taken in addition to your current medication. If willing, we also ask that you complete a blood test at the start of the study.
Each month you will be required to attend study visits (7 visits in total) at The Melbourne Clinic in Richmond. You will meet with one of the researchers for approximately 60 minutes (the initial session may take up 90-120 mins) and complete questionnaires regarding your OCD symptoms, mood, anxiety and quality of life.
You may be eligible to participate if you:
- Are between the age of 18-70
- Have been diagnosed with Obsessive-Compulsive Disorder (OCD)
- Are currently taking medication for your OCD but still experience symptoms
The study capsules and blood test involved in the study are free of charge. You will receive Coles Myer gift vouchers throughout the 6-month study period totaling $140 as well as 3 containers of complementary NAC at the end of your participation in the study.
GREEN Tea (L-theanine) for the treatment of Generalised Anxiety Disorder
The University of Melbourne is currently conducting a 10-week clinical trial investigating the effects of
L-theanine for Generalised Anxiety Disorder (GAD). L-theanineis the most abundant amino acid present in green and is believed to relieve anxiety, stress and improve focus and attention. However, there are minimal research studies exploring the effects of L-theanine for GAD.
You may be eligible to participate if you are aged between 18 and 75 and are currently taking medication for your anxiety but you are still experiencing symptoms.
If eligible to participate, you will be required to take L-theanineor a placebo capsules daily for a period of 8-weeks (the last two-weeks of the study you will not be required to take any capsules) and attend 6 sessions at The Melbourne Clinic in Richmond. These sessions will be held each fortnight where you will meet with one of the study researchers and answer questions regarding your anxiety and general health. The initial session of the study may last approximately 90 minutes, whereas the following visits approximately 45 minutes each.
It is free to participate in this study. You will be given a total of $70 in the form of Coles Myer gift cards as reimbursement for any travel costs. A free sample of L-theanine will also be provided when you complete the study.
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